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4 HYDROXYCOUMARINS
Descriptors Found:
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DeCS
Descriptor
English
:
4-Hydroxycoumarins
Descriptor
Spanish
:
4-Hidroxicumarinas
Descriptor
Portuguese
:
4-Hidroxicumarinas
Synonyms
English
:
4 Hydroxycoumarins
Tree Number:
D03.383.663.283.446.520
D03.633.100.150.446.520
Definition
English
:
Substances found in many
plants
, containing the 4-hydroxycoumarin radical. They interfere with
vitamin K
and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal
enzymes
, and are used as oral
anticoagulants.
Indexing Annotation
English
:
/biosyn permitted if by plant
Pharmacological Action:
Anticoagulants
Enzyme Inhibitors
History Note
English
:
77
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7056
Unique Identifier:
D015110
Occurrence in VHL
:
Similar:
DeCS
CID-10
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